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Ugandan Knuckles is a VRChat meme built around a distorted 3D model of Knuckles the Echidna from the Sonic the Hedgehog franchise. Players swarmed virtual lobbies using the avatar while repeating "Do you know de wey?" in a mock African accent, creating one of the most viral and controversial gaming memes of early 2018. The meme sparked a major debate about racial stereotyping in online spaces and drew comparisons to Pepe the Frog's trajectory from harmless joke to co-opted symbol.

Keyboard Cat is a viral video meme featuring an orange tabby cat named Fatso, filmed in 1984 by performance artist Charlie Schmidt, appearing to play an electronic keyboard while wearing a blue shirt. The clip sat dormant for over two decades before being uploaded to YouTube in 2007 and exploding into one of the internet's most recognizable memes in 2009, when Brad O'Farrell created the "Play Him Off, Keyboard Cat" mashup format that paired the footage with fail videos as a comedic send-off.

Surprised Pikachu is a reaction image pulled from a 1997 episode of the Pokémon anime, showing Pikachu with wide eyes and an open mouth in a look of shock. First used as a meme on Tumblr in September 2018 by user popokko (Angela), it became the most-used meme of that year by pairing the image with scenarios where someone is "surprised" by a completely predictable outcome. A WIRED investigation into its viral trajectory raised questions about whether its November 2018 popularity spike was connected to the Detective Pikachu film marketing, though no definitive link was established.

"Change My Mind" is an exploitable image macro meme featuring conservative commentator Steven Crowder sitting behind a folding table with a sign inviting passersby to debate him. The original photo was taken at Texas Christian University on February 16, 2018, with the sign reading "Male Privilege is a Myth / Change My Mind"[4]. Within days, internet users began replacing the sign text with humorous, absurd, or satirical statements, turning a political debate segment into one of the most versatile opinion-sharing templates online[1].

Baby Yoda is the internet's nickname for Grogu, a tiny green alien character from the Disney+ series *The Mandalorian* who looks like an infant version of the iconic Star Wars Jedi Master Yoda. First revealed in the show's premiere on November 12, 2019, the character instantly broke the internet with an avalanche of memes, reaction images, and photoshops that made him one of the biggest memes of the year. Despite Disney officially naming him "The Child" and later revealing his canonical name as Grogu in Season 2, the internet overwhelmingly stuck with "Baby Yoda."

Modern Problems Require Modern Solutions is a reaction image meme featuring comedian Dave Chappelle pointing to his temple with a knowing expression. The screenshot comes from a 2004 episode of Chappelle's Show and went viral on Reddit in December 2018[2]. The format is used to caption clever, absurd, or questionable "solutions" to everyday problems.

"All Star" is a 1999 rock song by Smash Mouth that became one of the internet's most enduring memes after its prominent use in the 2001 animated film *Shrek*. The song's iconic opening line, "Somebody once told me," launched thousands of remixes, mashups, covers, and parodies across YouTube, Reddit, and beyond. Written as an anthem for outcasts by guitarist Greg Camp, the track found a second life online in the 2010s through creators like Neil Cicierega and Jon Sudano, and the band themselves leaned into the joke.

Nyan Cat is an 8-bit animated GIF of a cat with a cherry Pop-Tart body flying through space, trailing a rainbow, set to the endlessly looping Japanese Vocaloid song "Nyanyanyanyanyanyanya!" by daniwellP. Artist Christopher Torres created the animation during a Red Cross charity livestream on April 2, 2011; three days later YouTuber saraj00n paired it with the song, and the combination quickly became one of the biggest viral memes of the early 2010s. The original video pulled in over 205 million YouTube views and sparked games, merchandise, a Webby Award, and a landmark NFT sale worth nearly $600,000.